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Domenico Viglione Borghese (13 July 1877 – 26 October 1957) was an Italian operatic baritone and actor.
Born in Mondovì, he gave up his studies in medicine to dedicate himself to the study of singing, first in Milan and later with Luigi Leonesi at Conservatorio Rossini in Pesaro, where he was admitted in 1896. He made his début in 1899 at the Teatro Verdi in Lodi as the Herald in Lohengrin. Though he continued working in small, provincial theaters, he soon gave up opera, saying that he did not care "for the atmosphere and intrigues."
Shortly thereafter he emigrated to America to join the Klondike Gold Rush but was unsuccessful there. After about three years, he moved to San Francisco, where he worked as a bottle washer, waiter, as a navvy on the railroad, and on the docks. A 1904 San Francisco directory shows him residing at 700 Broadway in San Francisco's Chinatown. He continued taking lessons and singing here and there and by a stroke of fortune was heard by Enrico Caruso, who recommended to the impresario Scognamiglio that he engage Viglione Borghese in his traveling opera troupe, whose prima donna was Luisa Tetrazzini. He sang on their 1906–1906 tour of Mexico, the Caribbean, and South America and from his successes during these performances, he was able to return to Italy at the end of 1906 to pursue an operatic career once more.
His major stage debut was as Amonasro in a 1907 production of Aida at the Teatro Regio in Parma. The power and size of his voice created a sensation, and he soon was alternating Amonasro with Marcello in La bohème and Gerard in Andrea Chénier. About Viglione Borghese's impact on the Italian opera scene, Edgar Herbert-Caesari said: